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Antiproliferative effects of mitochondria-targeted N -acetylcysteine and analogs in cancer cells
10.1371/journal.pone.0089464 89 LiuH.ZhouY.BoggsS
received grants from the Ono Pharmaceutical Corporation during the study
This observation is not surprising considering the loss of function of pVHL in a number of renal cancers leading to stabilization of HIF- and subsequent pseudohypoxic possibly resulting in an increased activity of GCLC and GCLM
A series of 2 to 6 treatments may be recommended for optimal results, depending on the specific treatment and individual needs
Methods 11 , 6365 (2014)
