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MOTS-c is a mitochondria-derived peptide commonly discussed in research contexts around metabolic signalling, energy regulation, exercise response, and cellular resilience

For instance, in vitro co-cultures and synthetic gut microbiome communities have shown that riboflavin promotes cross-feeding networks involving butyrate production pathways 207,208

In macrophages, NLRP3 inflammasome activates caspase-1

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[DOI] [PubMed] [Google Scholar] 142.Crabb D.W., Bosron W.F., Li T.K

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