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Author contributions LC performed the experiments, contributed to experimental design, analyzed data and wrote the manuscript

Physiol Rev 2017;97:995-1043

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Then these cells were stimulated to M1-like or M2-like polarization and treated via different concentrations of SP (cells/mL, 1.2 10 6 , 2.5 10 6 , 5 10 6 , 1 10 7 ) for 24 h

A higher dose arm is set to begin in the second half of 2026

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