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J Physiotherapy

Our skin repairs itself, but this ability weakens over time

Tomou EM, Papakyriakopoulou P, Saitani EM, Valsami G, Pippa N, Skaltsa H
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Overall, non-enzymatic crosslinks, specifically AGEs, are physiologically relevant in tendon because of diabetes and aging

Besides, some other potential targets are also listed in this manuscript (Table 2)