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The results demonstrated that NaF activated the downstream PI3KAKT, MAPK, and FOXO pathways by regulating the BDNFTrkB pathway through SIRT1, inhibited cell proliferation, blocked the cell cycle, and promoted apoptosis

The Model group exhibited significantly higher fasting blood glucose levels (Figure 1C), HOMA-IR (Figure 1D) and FINS (Figure 1E), and ISI (Figure 1F) than that of the Control group

HbA1c, disease duration) and achieved AUC 0.81 in an independent test set, demonstrating utility in risk prediction rather than definitive diagnosis [58]

10.1073/pnas.91.9.4082 68 DaubJ

The Sillustani Puno Tour visits an ancient necropolis with funeral towers called chullpas , built by the Collas and later the Incas

Zhang Z-Y, Yang Y-H, Ding H, Wang D, Chen W, Lin H