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doi: 10.3390/insects15110876 97 SongZ.WangY.LiC.TanY.WuJ.ZhangZ

The PKR pathway becomes activated upon binding double-stranded RNA (dsRNA), leading to phosphorylation of eIF2, an event typically halting protein synthesis as part of an antiviral response

Intranasal delivery represents the most significant methodological advancement because it bypasses hepatic first-pass metabolism entirely, but technique sensitivity (nasal cavity anatomy, administration volume, head positioning post-dose) introduces reproducibility challenges that subcutaneous injection avoids

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10.1007/BF02969312 263 WeschawalitS.ThongthipS.PhutrakoolP.AsawanondaP

Recent studies have shown that bioactive peptides have protective effects on alcohol-induced liver damage [9]
