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conducted a placebo-controlled double-blind RCT on 180 females

The Effect of Berberine on Polycystic Ovary Syndrome Patients with Insulin Resistance (PCOS-IR): A Meta-Analysis and Systematic Review

Peer review Peer review information Nature Communications thanks the anonymous reviewer(s) for their contribution to the peer review of this work

Moreover, NAC can regulate cell cycle progression, inhibiting the induction of cyclin D and DNA synthesis, which would lead to a G1 arrest in phorbol ester-induced NIH 3 T3 cells [13]

doi: 10.1134/s0006297910030041

Hence, the reduction of the GSH level by both drugs might also reflect to some extent beginning tumor necrosis
