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[DOI] [PubMed] [Google Scholar] 246.Latzman JM, Kong L, Liu C, Samadani U

However, the loss of just PLC2 is sufficient to reduce ROS production to level slightly above resting cells (Li et al., 2000), suggesting that PLC2 is the primary mediator of superoxide production

76,77,78,79,80 Therefore, changes in the NADP/NADPH ratio may determine the sensitivity of ferroptosis, while ferroptosis-resistant cell lines may have higher basal NADPH levels or lower NADP/NADPH ratios

Claude Didierjean (Univ