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On the other hand GPx3 is negatively correlated with MAPK oncogenic signaling pathway (94), which suggests a potential antitumor effect in thyroid cancer, while a decrease in GPx3 levels predisposes to an increase in the size of primary tumors and the number of metastatic lymph nodes (95, 96)
2000 Retinoblastoma protein dephosphorylation is an early event of cellular response to prooxidant conditions FEBS Lett

The recently discovered anti-ferroptotic actions of some of the BD treatment is nothing but compelling to elucidate the interplay of ferroptosis molecular machinery and BD pathogenesis (Fig

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