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The Micheal-type addition, in which the , -unsaturated carbonyl group (as an electrophile) alkylate the biological nucleophiles (such as the SH group in cysteine), was thought to be responsible for the significant antiproliferative action of compounds containing , -unsaturated carbonyl, such as alantolactone and ISA (Lawrence et al., 2001

A glutation szintjt befolysol tnyezk A glutation szintje a szervezetben szmos kls s bels tnyez hatsra cskkenhet, ami negatvan befolysolhatja a sejtek mkdst

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It regulates GPX4-mediated GSH synthesis by interacting with CREB, suppressing GPX4 transcription, and enhancing ferroptosis sensitivity

Identification of molecular marker associated with ovarian cancer prognosis using bioinformatics analysis and experiments
