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This cascade activates caspase-9 and caspase-3, ultimately triggering apoptotic cell death
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They maintain the required antioxidant level in the body by reducing the level of peroxides and making nicotinamide adenine dinucleotide phosphate (NADPH) and glutathione available for the primary antioxidant enzymes
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In contrast, FeNO was negatively correlated with severity, significant only for the modified Reiff score (r = 0.181, p = 0.04)
