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1 They remark that inflammation centered on the bile ducts may be present, but is not a hallmark of the disease

This study was supported by the national program Young and Postdoctoral Scientists provided by Bulgarian Ministry of Science and Education

In addition, although Cys 2 uptake is essential for antioxidant protection of cancer cells against ferroptosis, Cys 2 transport through SLC7A11 can also induce oxidative stress and cell death in glucose-deprived glioblastoma cells (56)

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Besides, western blotting revealed a concentration-dependent decrease in the level of JAK2, p-JAK2, STAT3, p-STAT3, and GSTP1 after 24 h of treating LoVo cells with the specific inhibitor of JAK2 (AG490)