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Supplementation also delayed physical exhaustion in Wistar rats by 29% and improved antioxidant defenses, including mitochondrial superoxide dismutase and glutathione peroxidase activity in skeletal muscle [93]

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Effect of Combinations of ALA and Other Compounds on Female Pathologies: Clinical Studies A recent systematic review investigated the potential benefits of ALA in women with polycystic ovary syndrome (PCOS) and confirmed the improvement of different cardiometabolic factors (such as fasting blood sugarFBS and HOMA-IR) as well as hormonal parameters [148]