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Ask a doctor before using on children under 6 months of age For continued protection from mosquitoes, gnats, no-seeums, sand flies and biting midges, reapply after 8 hours For continued protection from deer ticks, reapply after 6 hours and from black flies, reapply after 3 hours For sunscreen protection, reapply as needed or after towel drying, swimming or sweating Do not exceed 4 applications per day 2

References Abu-Remaileh M, Wyant GA, Kim C, Laqtom NN, Abbasi M, Chan SH, Freinkman E, Sabatini DM (2017) Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

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Randomized, placebo-controlled trial of methyl B 12 for children with autism. Journal of child and adolescent psychopharmacology 26, no

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Mechanistic studies demonstrate that melanocytes in melasma lesions display increased expression of estrogen and other sex hormone receptors, with heightened sensitivity to hormonal stimulation, thereby accelerating pigment production and recurrence [19]