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Description
L-ascorbic acid isomers (Figure 1) erythorbic acid, known as D-araboascorbic acid, and D-ascorbic acid also have activity in the human body

The 1858 C/T SNP of the PTPN22 gene is a risk factor for HT because it causes an arginine-tryptophan substitution at codon 620 (R620W), because decreased T cell signaling may results in poorer thymic elimination of autoreactive T cells, or an increased function of PTPN22 may lead to a decrease in regulatory T cells (Tregs) responsible for preventing autoimmunity

2009 Jun 15;180(1):20-30

PMID: 38987173 bioRxiv Intestinal fructose metabolism drives unsaturated fat absorption and synergizes with GLP-1 receptor agonism to promote weight loss

Wang Y, Fu Z, Guan D, Zhao J, Zhang Q, Liu Q, et al

Prostate-specific antigen (PSA) and prostate assessment should be performed as recommended by BSSM guidelines and individual testosterone SmPCs before and during TRT
