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Inclusion complex of zerumbone with hydroxypropyl--cyclodextrin induces apoptosis in liver hepatocellular HepG2 cells via caspase 8/Bid cleavage switch and modulating Bcl2/Bax ratio

For apoptosis induction, Jurkat cells (20,000 cells per well) were incubated with soluble human Fas ligand (30 ng ml 1 , ALX-522-020, Enzo Life Sciences) for 24 h, and Pfa1 cells (1,500 cells per well) were co-incubated with mouse TNF (10 ng ml 1 ) and BV-6 (400 nM) for 24 h

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Gynecol Endocrinol 39:2242962

An eye cream study over 12 weeks in 41 women with photodamage showed GHK-Cu outperformed both placebo and vitamin K cream for reducing lines and wrinkles while improving overall appearance and increasing skin density