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doi: 10.1002/jms.1284 121 Morin-SardinS.JanyJ.-L.ArtigaudS.PichereauV.BernayB.CotonE.et al
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The majority of these involved targeting the IGF-1R, either with monoclonal antibodies (mAbs) causing internalization of the receptor, or by blocking the receptors tyrosine kinase domain activation using receptor tyrosine kinase inhibitors (RTKIs)
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