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A mutation in the E(Z) methyltransferase that increases trimethylation of histone H3 lysine 27 and causes inappropriate silencing of active Polycomb target genes

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Quantitation of the ion peaks chromatographs showed that these interconverted reaction products accumulate early at the course of the reaction, but their quantities decline thereafter

Cell 182(5):1093-1108.e18, 2020
