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All PDB structures underwent preprocessing including the addition of missing amino acid atoms and hydrogens, removal of solvent atoms, and hydrogen-bond network optimization and residue protonation based on predicted pKa values using the Protein Preparation Wizard 51 of Maestro Schrdinger Release 2018-1 [Maestro, Schrdinger, LLC, New York, NY, 2018]

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prpTDP-43 A315T -UeGFP mice, the CSMN reporter line with TDP-43 pathology, allowed cell-type specific responses of CSMN to NMN treatment to be assessed in vitro

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Despite the controversy, IF may enhance cardiometabolic health by promoting circulating HDL levels

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This may be related to the higher creatinine concentration and more muscle mass in men (34)

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