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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Giannoulis MG, et al

However, when food and waste material move more slowly through the digestive system, water is reabsorbed more extensively from the colon, potentially resulting in harder, drier stools that are difficult to pass

doi:10.1016/j.freeradbiomed.2007.01.022 Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Additionally, RNF43 , a gene that negatively regulates Wnt signaling, is often mutated in MSI-H ECs, further enhancing tumor growth