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Description
This shape is due to a loss of membrane, often from autoimmune hemolytic anemia or hereditary spherocytosis

Strong Evidence from Studies with Brachymorphic Mice and Pentachlorophenol that 1'-sulfoxysafrole Is the Major Ultimate Electrophilic and Carcinogenic Metabolite of 1'-hydroxysafrole in Mouse Liver

Wen CJ, Wu LX, Fu LJ, Shen DY, Zhang X, Zhang YW, Yu J, Zhou HH (2014) Preferential induction of CYP1A1 over CYP1B1 in human breast cancer MCF-7 cells after exposure to berberine
2022;22(8):e2200019

The improvement in SAM may in part be due to improvements in ATP, since that is the co-factor needed to convert methionine to SAM

It supports the function of immune cells involved in pathogen recognition, inflammation regulation, and tissue repair
