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The average weight loss after 72 weeks of treatment was 1520% (compared to 3.1% with a placebo), and 3057% of participants lost at least 20% of their body weight [118]
Theres an anti-inflammatory pathway that it works through, he says

Step 3: MTHF releases its methyl group via vitamin B12 to the methionine cycle, which produces THF again and restarts the cycle

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Cyanocobalamin is the cheapest synthetic form, common in over-the-counter supplements
