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However, despite these promising prospects, the clinical application of ALA remains limited by its low bioavailability and chemical instability and an incomplete understanding of its multifaceted mechanisms across various diseases

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Additionally, SFN combined with 5-aza-2-deoxycytidine and trichostatin A significantly reduced the CpG methylation levels in the NRF2 promoter region and inhibited the protein expression of DNA methyltransferase 1 (DNMT1), thereby promoting NRF2 expression, which may play a preventive role in colon cancer [151]

Okra polysaccharides can improve memory function, reverse metabolic disorder and cognitive impairment through the insulin signaling pathway (Yan et al., 2020)

Gently swirl or roll instead