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48 In addition to regulating the above pathways to inhibit the inflammatory response, Quercetin can also regulate the Notch1, 54 SCAP/SREBP2/NLRP3, 55 PTEN/-catenin, AKT/GSK-3, 53 TLR4/Myd88, 56 and Nrf-2/ARE pathways 57 to reduce the release of inflammatory factors and mediators, thereby exerting anti-inflammatory effects and thus attenuating septic lung injury

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This shows lysine acetylation sites distributed over almost the entire SnCE1 protein, i.e., AcK94, AcK98 and AcK103 in the N-terminal region and AcK157, AcK172, AcK223, AcK231, AcK237 and AcK289 in the central and C-terminal part of the SnCE1 protein (Fig