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Keep a symptom diary noting the timing, severity, and location of joint pain, along with any potential triggers or relieving factors

employed in osteoarthritis and cartilage regeneration research Pigs Used for pharmacokinetic profiling and oral bioavailability studies Cynomolgus monkeys 9-month chronic toxicology studies via oral gavage Human subjects Approximately 900 participants across six clinical trials examining safety and efficacy Research Limitations & Regulatory Status Critical Gaps in Current Evidence Despite over 25 years of research and extensive clinical testing, AOD-9604 faces substantial evidence gaps that have prevented therapeutic development

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MOTS-c improves mitochondrial function for improved energy use, while FTPP causes fat cell death

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[1] In a 12 week randomised clinical trial, subjects receiving AOD9604 lost, on average, 1.8 kg more than those receiving placebo