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For example, a study on the co-encapsulation of astaxanthin and kaempferol demonstrated that, compared to nanoparticles encapsulating astaxanthin alone, the combined formulation exhibited significantly stronger antioxidant activity and lipid-regulating gene expression in RAW264.7 and HepG2 cells, indicating a pronounced synergistic effect (90)
Zhou, H
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doi: 10.5021/ad.2013.25.2.218 [DOI] [PMC free article] [PubMed] [Google Scholar] 19.Kim YM, Cho SE, Kim SC, Jang HJ, Seo YK
10.1111/ijd.15133 15 BaileyA
Pregnancy and breastfeeding are clear contraindications - we lack sufficient safety data on high-dose IV administration during these times
