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The enlarged LAMP1 + compartment phenotype in Munc13-4-KO was rescued by the expression of Munc13-4 but not by the expression of Munc13-4-C2A*C2B*, a mutant that disrupts its interaction with STX7 (ref

Not surprisingly, the trend of recommending and administering intravenous glutathione has increased within months of it becoming available, despite the potential adverse effects and lack of evidence

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Frisch J, Venkatesan JK, Rey-Rico A, Schmitt G, Madry H, Cucchiarini M