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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Kapetanaki S, Kumawat AK, Persson K, Demirel I

Calcium released in the cytoplasm causes cytoplasmic PKC to translocate to the plasma membrane while calcium that is released within the nucleus translocates nuclear PKC to the nuclear envelope.79 Also, there are separate pools of DAG produced by phospholipids localized within the cytoplasm or the nucleus.80 Furthermore, stimulusdependent production of DAG leads to selective translocation of specific PKC isoforms to the nucleus
anesthesia was not necessary or used as the clustered worms rapidly became hypoxic and stopped moving

Another reason is that it is simpler to store, with only one vial, and minimalists often prefer the lack of extraneous components
Data was collected by the study group, and analyzed by the authors with the help of the sponsor

(2017) indicate that metabolic activation plays a crucial role in citalopram-induced hepatotoxicity
