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Ethics declarations Acknowledgements The authors are grateful to the multidisciplinary team of dedicated nurses, dietitians, psychosocial workers and physicians at the Diabetes Center at Dana-Dwek Childrens Hospital, and to E

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Further, the periodic introduction of decreased maintenance doses during 2-3 months or for life is possible

Stepwise addition of the FOXO4-DRI peptide to this complex caused the CSPs of FOXO4 to be reverted back to the unbound state, indicating FOXO4-DRI competes with FOXO4 for p53 binding in a dose-dependent manner and doing so with higher affinity (Fig

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