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Appel L, Bergstrom M, Buus Lassen J, Langstrom B Tesofensine, a novel triple monoamine re-uptake inhibitor with anti-obesity effects: dopamine transporter occupancy as measured by PET

Researchers study it to understand how the body produces its own sleep-promoting substances and how these might interact with stress systems in experimental settings

10.1089/neu.2019.6854 J

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Mar 2020;9(Suppl 2):S206-S214

The Wnt ligand Wnt7a is essential in multiple steps of adult hippocampal neurogenesis and regulates these processes by activating downstream target genes of the canonical Wnt--catenin pathway that are involved in cell cycle control under proliferating conditions (e.g., cyclin D1 ) and those involved in neuronal differentiation upon differentiation ( Neurogenin2 ) [55]