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In addition, the treatment of nicotinamide (NAM), a form of vitamin B3, suppressed the activity of sirtuin-1 (SIRT1), a regulator of cellular stress resistance, and peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1), a key transcriptional coactivator involved in mitochondrial biogenesis and energy metabolism

Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo

P -values are represented as * p 0.05, ** p 0.01, *** p 0.001, **** p 0.0001

Over-the-counter products or home remedies can cause side effects

In addition, specific amino acid deficiency or the immunosuppressive effect of certain amino acid metabolism can damage the function of immune cells, including effector T cells, in the tumor microenvironment

[DOI] [Google Scholar] 872.Ohgami K., Shiratori K., Nitta T., Shinmei Y., Chin S., Yoshida K., Tsukahara H., Ohno S