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Also, the metal ion doping (Fe 3+ , Mn 2+ , Zn 2+ ) or incorporating fluorescent dyes into the silica structure provides magnetic or optical capability to image and treat diseases [47]

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In summary, schisandrin lignans appear to protect dopaminergic neurons by a combination of antioxidant, anti-excitotoxic, anti-inflammatory, and pro-autophagic mechanisms, making them interesting candidates for further neuroprotective research

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SLN has the advantages of enhanced drug penetration, targeted delivery, loading of amphiphilic drugs, and protection from hepatic clearance for safe transportation and improved drug efficacy (Mishra et al., 2018)

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Hum Microbiome J

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Jacinto-AzevedoBValderramaNHenrquezKArandaMAquevequeP

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10.1152/jappl.1999.87.4.1381 42

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