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Consistently, in clinical studies, loss of EZH2, upregulation of KDM6 and reduced H3K27 Me3 are associated with multiple drug resistance and poor prognosis of AML patients (Gollner et al., 2017

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i.KitamiT.NodaS.ShimuraH.UchiyamaY.AsakawaS.et al (2001)

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