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However, the mechanism of action of this peptide remains to be further elucidated

Semaglutide targets the GLP-1 receptor, whereas tirzepatide targets both GLP-1 and GIP receptors

[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Song, Q

At the same time, endothelial cell senescence also affects the delivery of nutrients and oxygen, leading to metabolic abnormalities and further accelerating organismal aging (Boutouyrie et al., 2021

doi: 10.1038/nrm4007