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A growing body of research has revealed that ferroptosis plays significant pathogenetic roles in cancer, ischemia organ damage, and dementia since it was first used by Dixon et al

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2017;108(Pt A):33950

For CCK-8 analysis, macrophages or chondrocytes were seeded in 96-well plates at a density of 5 10 cells/well and exposed to Se/LDH@PEG-M at different concentrations for 2472 h

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The regulation of programmed cell death (PCD) is a crucial determinant of cell fate (127), and studies have demonstrated that copper overload can induce various forms of PCD in cells