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and the use of antivirals that enhance activation of the Nrf2 transcription factor together with N-acetylcysteine administration restore GSH levels correcting the SARS-CoV-2-mediated impaired GSH metabolism (Aquilano et al., 2014

S-Adenosylmethionine Inhibits La Ribonucleoprotein Domain Family Member 1 in Murine Liver and Human Liver Cancer Cells

GCLM polymorphism has been associated with impairment of NO-mediated coronary vasomotor function and risk of myocardial infarction (Nakamura et al., 2002

Redox Biol 34:101550

Aggravated accumulation of S disrupts mitochondrial biogenesis and function by dysregulating the AMPK-CREB-PGC-1 pathway (Shi et al., 2005), which regulates Sirt3 and mitochondrial defence (Park et al., 2020), reported that restoration of Sirt3 expression through the AMPK agonist 5-aminoimidazole-4-carboxamide riboside (AICAR) could recover mitochondrial dynamics and mitophagy
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