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This structural modification has made IGF-DES an important research compound for understanding the role of binding proteins in modulating IGF-1 activity

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As an apex predator in many aquatic ecosystems, it is an air-breathing and tropical carnivorous freshwater fish, belonging to the family Ophiocephalidae or Channidae 5 that can sustain low dissolved oxygen levels and hence suitable for climate-resilient aquaculture 6

Other studies have also confirmed the importance of the p38 MAPK signaling pathway and its regulators, including pmk-1 , sek-1 (encodes MAPKK), nsy-1 (encodes MAPKKK), and tir-1 (toll-interleukin repeat protein