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Both loss and gain of functions have been proposed for mutant TDP-43 and mutant FUS, whereas gain of a toxic function is the preferred mechanism associated with mutant SOD1

is developing HGF mimetics and antagonists for the treatment of various disorders including dementia

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The peak fractions were collected and applied to HiTrap SP HP (Cytiva) for further purification

Catalase (CAT) is an enzyme in the oxidoreductase group

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