glutathione and gaba shunt pathways. GABA is synthesized from glutamate either directly Proof of principle: GSH (A),

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Neuropsychopharmacology 38:504512 Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, Defalco L, Andolfo I (2019) Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of -thalassemia

doi: 10.1016/j.celrep.2017.10.090 47 TekgucMWingJBOsakiMLongJSakaguchiS

[14] found that mice with NNMT knockdown have lower levels of fasting glucose and lower pyruvate conversion to glucose compared to control mice

Alabdali A, Al-Ayadhi L, El-Ansary A (2014) A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders

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