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Gut Microbiota and Atherosclerosis Atherosclerosis is the major risk factor for CVD, which is characterized by accumulation of cholesterol and recruitment of macrophages into artery walls, contributing to the formation of atherosclerotic plaques ( Roseburia and Eubacterium was lower, while Collinsella was higher in atherosclerosis patients compared to healthy controls ( Akkermansia muciniphila was found to improve gut barrier functions and exert protective effects against atherosclerosis ( Gut Dysbiosis and Inflammation in Atherosclerosis Inflammation is commonly involved in a number of diseases ( Lipopolysaccharide is a cell wall component of Gram-negative [G()] bacteria, which has been extensively studied as it is one of the PAMPs involved in CVD risk