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10.1124/dmd.113.054254 17 SikiricP.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)

The compound interacts with monomeric protein, while remodeling and disrupting oligomeric and fibrillar structures, thus precluding the formation of toxic species [271]
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HUBERMAN: And while not always successful, it was clear
Subcutaneous administration achieves similar bioavailability while avoiding deeper tissue penetration
