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also observed similar phenomena in the testes of STZ-induced diabetic mice and HG-treated GC-1spg cells, and found that BRD7 inhibits Clusterin expression by regulating hypermethylation of the Clusterin promoter in an EZH2-dependent manner, thereby suppressing AMPK signaling to promote ferroptosis and induce DM-related testicular injury [178]

Zhang et al., 2024)

doi: 10.1038/s41467-024-50222-2

Peng J, Wang Q, Sun R, Zhang K, Chen Y, Gong Z

doi: 10.1016/j.jprot.2015.04.005