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doi: 10.3389/fphys.2021.712338

However, although computational models can offer useful predictions, their translation to practice must be followed by in vitro and in vivo testing, and pharmacokinetic issues of poor solubility and bioavailability of natural compounds should be taken into account [12, 320]

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After washing three times with PBS/T, the plate was incubated for 1 h with StrepMAB-Classic HRP (mouse anti- Strep -tag HRP conjugate
Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy