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The strongest data comes from Harshini Neelakantan, Stan Watowich, and colleagues at the University of Texas Medical Branch (UTMB)

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Washington D.C.: National Academy Press

Vitamin B12 Essentials 2.1 Biochemical Roles and Neurological Importance Vitamin B12 (cobalamin) is indispensable for two biochemical pathways: Methionine Synthase : Converts homocysteine to methionine, fueling methylation reactions vital for DNA synthesis, neurotransmitter production (serotonin, dopamine), and myelin maintenance