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[DOI] [PubMed] [Google Scholar] 380.Licata A, Di Bona D, Schepis F, Shahied L, Craxi A, Camma C

It has already been demonstrated that the expression levels of GCK are positively associated with intrahepatocellular lipids and de novo lipogenesis ( in vitro that the oxidative damage of cells induced by extracellular hyperglycemia was caused by enhanced GCK activity ( Therefore, we hypothesized that GCK inactivating mutation may confer protective effects against atherosclerosis through the following mechanisms

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Adam Friedman, MD, is a professor and chair of dermatology at The George Washington University School of Medicine & Health Sciences in Washington, D.C