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The two co-primary endpoints were analyzed independently of each other, and for the trial to be considered to be positive (indicating a significant benefit of semaglutide versus placebo), statistical superiority for both co-primary endpoints was required to be demonstrated

At 10 mg/mL, accuracy becomes critical

(2020, September 19)

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However, if it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule