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After evaluating the best candidate, we then showed that ES2 colocalized to FOXO4 foci and preferentially bound FOXO4 over TP53

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10.1056/NEJM199409083311003 70 FujisawaT.ChangM.M.-J.VelichkoS.ThaiP.HungL.-Y.HuangF.et al (2011)

Barrier Analysis - High Treatment and Manufacturing Costs The intricate manufacturing processes and the need for personalized treatments make regenerative therapies costly