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[DOI] [PubMed] [Google Scholar] Geier DA, Geier MR

Conversely, under conditions that favor cell growth and proliferation, ERK1/2 may suppress autophagy by promoting mTOR activity via the TSC2/Rheb/mTORC1 axis, a mechanism that is particularly prominent in cancer (155) and is also implicated in neurodegenerative disorders (156)

However, the concrete role of GLS2 in tumors remains unclear, although some studies showed that it may inhibit tumor growth in some cancers (Liu et al., 2014

These substances draw additional immune cells to the damaged kidneys

Studies have shown that Isofraxidin can inhibit ferroptosis by upregulating Nrf2 and reducing ROS levels

Most critically, NAC strongly potentiates the effects of nitroglycerin and other nitrate vasodilators