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This work was supported by Basic Scientific Research Fund of Education Department of Liaoning Province, China (LJ212410161100 to Z-LL), Natural Science Foundation of Liaoning Province, China (2022-MS-326 to Z-LL), and Dalian Medical University's "Integrated Traditional Chinese and Western Medicine " Open Fund Project (ZXY2025JC04 to Z-LL)

, Kizivat, T

These molecular perturbations collectively contribute to chronic inflammation, genomic instability, and the malignant transformation of hepatocytes

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Superimposed sequence chromatograms produced by biallelic and heterozygous mutations were decoded by DSDecode ( and manual analyses

The mechanical delivery eliminates the need to simultaneously stabilize the device and push a plunger