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Limonene-enriched ultra-structural cubosomes to augment ocular delivery of a poorly water soluble anti-fungal drug: Fabrication, characterization, statistical optimization, in vivo corneal uptake and histopathological evaluation in rabbits

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Marked efficacy differences between antidiabetic phytocompounds and their PLGA-based nanoformulations can be ascribed to the specialized uptake of NPs through payers patches via M-Cells into lymphatic system and then directly into systemic circulation and thus avoiding first-pass metabolism

doi: 10.3390/ijms23137292

Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways